This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognizing you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful. Check our privacy policy here.
GalChimia has special internal R&D programs, where we focus our efforts on the chemical synthesis of complex and challenging compounds. This allows the company to discover many new applications for our chemistry in fields the company does not usually explore.
Publications
- EST64454: a Highly Soluble σ1 Receptor Antagonist Clinical Candidate for Pain Management. J. Med. Chem. 2020. DOI: 10.1021/acs.jmedchem.0c01575.
- Identification of 6-amino-1H-pyrazolo[3,4-d]pyrimidines with in vivo efficacy against visceral leishmaniasis. RSC Med. Chem. 2020,11, 1168–1177.
- Optimisation of a key cross-coupling reaction towards the synthesis of a promising antileishmanial compound. Tetrahedron Lett. 2019, 60(18), 1243–1248.
- Adsorption of Pharmaceutical Pollutants from Water Using Covalent Organic Frameworks. Chem. Eur. J. 2018, 24(42), 10601-10605.
- A Positive Allosteric Modulator of the Serotonin 5-HT2C Receptor for Obesity. J. Med. Chem., 2017, 60 (23), 9575–9584.
- Selective copper-promoted cross-coupling reaction of anilines and alkylboranes, Tetrahedron Lett. 2012, 53(7), 769–772.
- Design of Experiments has far wider use than simply optimising yields, Speciality Chemicals Magazine 2011, 3, 18–19.
- 清野菜名英文清野菜名英文,色戒未删除班色戒未删除班Selective Monomethylation of Anilines by Cu(OAc)2-Promoted Cross-Coupling with MeB(OH)2, Org. Lett. 2009, 11(8), 1677–1680.
- Selective Copper-Promoted Cross-Coupling of Aromatic Amines with Alkyl Boronic Acids, Synlett 2010(14), 2101–2105.
- Microwave-assisted aza-Cope rearrangement of N-allylanilines, Tetrahedron Lett. 2008, 49(12), 2002–2004.
Posters and White Papers
Napropamide impurities and metabolites: a complementary approach using chemical synthesis and biosynthesis
Our collaboration with Hypha Discovery for the preparation of a comprehensive family of napropamide derivatives
Design and Synthesis of linkers for Glycan-Coated Gold Nanoparticles Used in Drug Discovery
Pampín, B.; Codesido, E.; Masse, J.; Cruces, J.
Patents
- WO 2016078770 (A1) – Preparation of spiro-isoquinoline-1,4′-piperidine compounds having multimodal activity against pain
- WO 2014177517 (A1) – Preparation process of an agonist of the thrombopoietin receptor清野菜名英文清野菜名英文,色戒未删除班色戒未删除班
- WO 2011147910 (A1) – Pyrazole compounds as sigma receptor inhibitors
- WO 2011051452 (A1) – N-Containing heteroaryl derivates as JAK3 kinase inhibitors
- WO 2009115393 (A1) – Process for the preparation of N-(Phenilethyl) Anilines salts an solvates thereof useful as serotonin 5-HT6 antagonists
- US 7879912 (B2) Process for preparing 3,3-Diarylpropylamines